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Invitrogen™ Plasminogen Monoclonal Antibody (H16), Invitrogen™
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Catalog No. PIMA543960
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100 μL
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PIMA543960 100 μL
PIMA543961 20 μL
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Catalog No. PIMA543960 Supplier Invitrogen™ Supplier No. MA543960
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Description

Mouse Monoclonal Antibody

Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200 mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Plasminogen
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone H16
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene PLG
Gene Accession No. P00747
Gene Alias Ab1-346; Activation peptide; AI649309; angiostatin; DKFZp779M0222; Pg; plasmin; plasmin heavy chain A; Plasmin heavy chain A, short form; Plasmin light chain B; plasminogen; PLG; RP1-81D8.1
Gene Symbols PLG
Host Species Mouse
Immunogen Native protein, with N-terminal His Tag.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5340
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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