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Plasminogen Mouse anti-Human, Clone: 1F6A11, Proteintech
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Catalog No. 501736827 Shop All Proteintech Group Inc Products
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50-173-6827 150 μL
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Catalog No. 50-173-6827 Supplier Proteintech Group Inc Supplier No. 663991IG150UL
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Mouse Monoclonal Antibody

Plasmin (PLG, Plasminogen) dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Plasmin binds to cells.

Specifications

Antigen Plasminogen
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1F6A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PLG
Gene Accession No. P00747
Gene Alias Angiostatin, plasminogen, PLG
Gene Symbols PLG
Host Species Mouse
Immunogen Plasminogen Fusion Protein Ag9938
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5340
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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