Invitrogen™ Plasminogen Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA143063

Catalog No. PIPA143063

Description

PA1-43063 detects Plasminogen in mouse samples. PA1-43063 has successfully been used in Western blot and ELISA applications. PA1-43063 was derived from mouse plasminogen.

Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200 mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.

Specifications

• Antigen: Plasminogen
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLG
• Gene Alias: Ab1-346; Activation peptide; AI649309; angiostatin; DKFZp779M0222; Pg; plasmin; plasmin heavy chain A; Plasmin heavy chain A, short form; Plasmin light chain B; plasminogen; PLG; RP1-81D8.1
• Host Species: Sheep
• Purification Method: SDS-PAGE
• Regulatory Status: RUO
• Gene ID (Entrez): 18815, 5340, 85253
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 6.9 mg/mL
• Formulation: 50% water with 50% glycerol and no preservative
• Gene Accession No.: P00747, P20918, Q01177
• Gene Symbols: PLG
• Immunogen: Murine Plasminogen.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG