Invitrogen™ PLB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120091

Catalog No. PIPA5120091

Description

Positive test controls include: A-431, U-87MG, HL-60, HT-29, Mouse testis, Mouse lung, Mouse skeletal muscle, Rat testis. The target is usually found in the following locations: Apical cell membrane, Single-pass type I membrane protein. Immunogen sequence: ARPNNSSDLP TSWRGLSWSI GGDGNLETHT TLPNILKKFN PYLLGFSTST WEGTAGLNVA AEGARARDMP AQAWDLVERM KNSPDINLEK DWKLVTLFIG VNDLCHYCEN PEAHLATEYV QHIQQALDIL SEELPRAFVN VVEVMELASL YQGQGGKCAM LAAQNNCTCL RHSQSSLEKQ ELKKVNWNLQ HGISSFSYWH QYTQREDFAV VVQPFFQNTL TPLNERGDTD LTFFSEDCFH FSDRGHAEMA IALWNNMLEP VGRKTTSNNF THSRAKLKCP SPESPYLYTL RNSRLLPDQA EEAPEV.

This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.

Specifications

• Antigen: PLB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLB1
• Gene Alias: 4632413E21Rik; 4930433E17Rik; 4930539A06Rik; BC033606; hPLB; Lysophospholipase; Phlpb; Phospholipase A2; phospholipase B; Phospholipase B/lipase; phospholipase B1; phospholipase B1, membrane-associated; PLB; PLB/LIP; PLB1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 151056, 192259, 665270
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.56 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O54728, Q3TTY0, Q6P1J6
• Gene Symbols: PLB1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov