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PLC-gamma 1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563860
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50-156-3860 20 μL
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Catalog No. 50-156-3860 Supplier Bethyl Laboratories, Inc Supplier No. A302940AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).

Specifications

Antigen PLC-gamma 1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PLCG1
Gene Accession No. P19174, Q62077
Gene Alias NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Gene Symbols PLCG1
Host Species Rabbit
Immunogen Between 1240 and 1290
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18803, 5335
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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