Invitrogen™ PLCD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532099

Catalog No. PIPA532099

Description

Recommended positive controls: HCT116. Predicted reactivity: Mouse (84%), Rat (82%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.

Specifications

• Antigen: PLCD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLCD3
• Gene Alias: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; 2610205J15Rik; Kiaa1964; mKIAA1964; phosphoinositide phospholipase C-delta-3; phospholipase C delta 3; phospholipase C, delta 3; phospholipase C-delta-3; PLC delta3; Plcd3; PLC-delta-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113026
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8N3E9
• Gene Symbols: PLCD3
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 349 and 589 of Human PLCD3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov