Invitrogen™ PLCL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556879

Catalog No. PIPA556879

Description

Immunogen sequence: LRYLVSRSKQ PLDFMEGNQN TPRFMWLKTV FEAADVDGNG IMLEDTSVEL IKQLNPTLKE AKIRLKFKEI QKSKEKLTTR VTEEEF Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.

Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.

Specifications

• Antigen: PLCL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLCL1
• Gene Alias: 130kDa-Ins(1,4,5)P3 binding protein; C230017K02Rik; inactive phospholipase C-like protein 1; p130; phospholipase C like 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; PLCE; PLCL; PLC-L; PLCL1; PLC-L1; PLDL1; PPP1R127; PRIP; PRIP1; PRIP-1; protein phosphatase 1, regulatory subunit 127
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5334
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15111
• Gene Symbols: PLCL1
• Immunogen: Recombinant protein corresponding to Human PLCL1. Recombinant protein control fragment (Product #RP-96032).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov