PLCL1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550730

Catalog No. PA550730

Description

The antibody detects endogenous levels of total PLCL1 protein.

Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintece of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.

Specifications

• Antigen: PLCL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLCL1
• Format: Liquid
• Gene Symbols: PLCL1
• Immunogen: Synthetic peptide corresponding to residues near the N terminal of human phospholipase C-like 1
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 2.8 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
• Gene Accession No.: Q15111
• Gene Alias: PLCE, PLCL, PRIP, PLDL1, PPP1R127
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 5334