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Invitrogen™ PLCL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550730

Catalog No. PA550730


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Description

Description

The antibody detects endogenous levels of total PLCL1 protein.

Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PLCL1
Polyclonal
Unconjugated
PLCL1
130kDa-Ins(1,4,5)P3 binding protein; C230017K02Rik; inactive phospholipase C-like protein 1; p130; phospholipase C like 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; PLCE; PLCL; PLC-L; PLCL1; PLC-L1; PLDL1; PPP1R127; PRIP; PRIP1; PRIP-1; protein phosphatase 1, regulatory subunit 127
Rabbit
Antigen Affinity Chromatography
RUO
5334
-20°C
Liquid
Immunohistochemistry (Paraffin)
2.8 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q15111
PLCL1
Synthetic peptide corresponding to residues near the N terminal of human phospholipase C-like 1.
100 μL
Primary
Human
Antibody
IgG
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