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Invitrogen™ PLD2 Polyclonal Antibody
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Catalog No. PIPA582482
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100 μL
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PIPA582482 100 μL
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Catalog No. PIPA582482 Supplier Invitrogen™ Supplier No. PA582482
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CFGVILGANT RPDLDLRDPI CDDFFQLWQD MAESNANIYE QIFRCLPSNA TRSLRTLREY VAVEPLATVS PPLARSELTQ VQGHLVHFPL KFLEDESLLP Highest antigen sequence indentity to the following orthologs: Rat - 85%, Mouse - 86%.

PLD2 is a peripheral membrane protein belonging to phospholipase D family with a PH domain, two PLD phosphodiesterase domains and a PX (phox homology) domain that plays a regulatory rather than catalytic role. PLD2 catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation and/or endocytosis, transcriptional regulation, and cell cycle control. It is usually stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by the ADP-ribosylation factor-1 (ARF-1). PLD2 is activated by agonist stimulation of both tyrosine kinase and G protein-coupled receptors and is also known to interact with EGFR and PIP5K1A. PLD2, localized to plasma membrane caveolae, is ubiquitously expressed in most tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLD2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pld2
Gene Accession No. O14939
Gene Alias choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; phospholipase D2; PLD 2; PLD1C; PLD2; Pldc; rPLD2
Gene Symbols Pld2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PLD2. Recombinant protein control fragment (Product #RP-90753).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5338
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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