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Invitrogen™ Plectin Polyclonal Antibody
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Catalog No. PIPA517156
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100 μL
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Catalog No. Quantity
PIPA517156 100 μL
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Catalog No. PIPA517156 Supplier Invitrogen™ Supplier No. PA517156
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. The expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development and it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms which carry out distinct and specific functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Plectin
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Plec
Gene Accession No. Q15149
Gene Alias AA591047; AU042537; EBS1; EBSMD; EBSND; EBSO; EBSOG; EBSPA; HD1; Hemidesmosomal protein 1; LGMD2Q; PCN; Plec; PLEC1; PLEC1b; Plectin; plectin 1; plectin 1, intermediate filament binding protein 500kDa; plectin-1; Plectin-6; Pltn
Gene Symbols Plec
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the central sequence of human plectin-1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5339
Target Species Human, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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