Plectin Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304506AT

Catalog No. 50-156-7893

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. The expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development and it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms which carry out distinct and specific functions.

Specifications

• Antigen: Plectin
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q15149, Q9QXS1
• Gene Symbols: PLEC
• Immunogen: Between 4534 and 4684
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PLEC
• Gene Alias: EBS1, EBSMD, EBSND, EBSO, EBSOG, EBSPA, epidermolysis bullosa simplex 1 (Ogna), HD1, hemidesmosomal protein 1, LGMD2Q, PCN, PLEC1, PLEC1b, plectin 1, intermediate filament binding protein 500kDa, plectin 1, intermediate filament binding protein, 500kD, Plectin-1, PLTN
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18810, 5339
• Content And Storage: 4° C
• Form: Liquid