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Plectin Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501567893
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50-156-7893 20 μL
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Catalog No. 50-156-7893 Supplier Bethyl Laboratories, Inc Supplier No. A304506AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans. The expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development and it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms which carry out distinct and specific functions.

Specifications

Antigen Plectin
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PLEC
Gene Accession No. Q15149, Q9QXS1
Gene Alias EBS1, EBSMD, EBSND, EBSO, EBSOG, EBSPA, epidermolysis bullosa simplex 1 (Ogna), HD1, hemidesmosomal protein 1, LGMD2Q, PCN, PLEC1, PLEC1b, plectin 1, intermediate filament binding protein 500kDa, plectin 1, intermediate filament binding protein, 500kD, Plectin-1, PLTN
Gene Symbols PLEC
Host Species Rabbit
Immunogen Between 4534 and 4684
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18810, 5339
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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