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Invitrogen™ PLEKHG7 Polyclonal Antibody
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Catalog No. FEPA5144820
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100 μL
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Catalog No. Quantity
FEPA5144820 100 μL
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Catalog No. FEPA5144820 Supplier Invitrogen™ Supplier No. PA5144820
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IKEGGSCTVL DQPIPLDRLV VKSIEPLHVS VFGLRNAFLI QHENRYRQCI AAFLLQAQTE NIKKTWMAQI TTAISCFTKS QETKKI Antigen sequence identity: Mouse 23%; Rat 22%.

The PLEKHG7 gene (Pleckstrin Homology and RhoGEF Domain Containing G7) encodes a protein that is a member of the Rho guanine nucleotide exchange factor (RhoGEF) family. This protein is involved in the regulation of the Rho family of GTPases, which play a critical role in multiple cellular processes including cytoskeletal organization, cell migration, and cell proliferation. The pleckstrin homology (PH) domain of PLEKHG7 allows it to interact with phosphoinositides, which helps localize the protein to cellular membranes where it can activate Rho GTPases. Dysregulation of PLEKHG7 has been implicated in certain cancers, highlighting its importance in cell signaling and cancer biology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLEKHG7
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PLEKHG7
Gene Accession No. Q6ZR37
Gene Alias PH domain-containing family G member 7; pleckstrin homology and RhoGEF domain containing G7; pleckstrin homology domain containing, family G (with RhoGef domain) member 7; pleckstrin homology domain-containing family G member 7; PLEKHG7
Gene Symbols PLEKHG7
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 594-679. Recombinant protein control fragment (Product #RP-97882).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 440107
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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