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Invitrogen™ PLEKHM2 Polyclonal Antibody
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Catalog No. PIPA556946
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100 μL
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PIPA556946 100 μL
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Catalog No. PIPA556946 Supplier Invitrogen™ Supplier No. PA556946
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GTQEVLCQLK RDQPSPCLSS AEDSGVDEGQ GSPSEMVHSS EFRVDNNHLL LLMIHVFREN EEQLFKMIRM STGHMEGNLQ LLYVLLTDCY VYLLRKGATE KPYLVEEAVS YNELDYVSV Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.

PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLEKHM2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PLEKHM2
Gene Accession No. Q8IWE5
Gene Alias 2310034J19Rik; AI854247; KIAA0842; mKIAA0842; novel RUN and PH domain-containing protein; PH domain-containing family M member 2; pleckstrin homology and RUN domain containing M2; pleckstrin homology domain containing, family M (with RUN domain) member 2; pleckstrin homology domain-containing family M member 2; Plekhm2; RP11-169K16.1; Salmonella-induced filaments A and kinesin-interacting protein; SifA (Salmonella-induced filaments A) and kinesin-interacting protein; sifA and kinesin-interacting protein; SKIP
Gene Symbols PLEKHM2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PLEKHM2. Recombinant protein control fragment (Product #RP-100983).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23207
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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