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Invitrogen™ PLEKHM3 Polyclonal Antibody
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Catalog No. PIPA520851
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100 μg
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Catalog No. Quantity
PIPA520851 100 μg
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Catalog No. PIPA520851 Supplier Invitrogen™ Supplier No. PA520851
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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse skeletal muscle tissue lysate. PA5-20851 can be used with blocking peptide PEP-0965.

PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLEKHM3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PLEKHM3
Gene Accession No. Q6ZWE6, Q8BM47
Gene Alias 9430067K14Rik; A230102O09Rik; AI449570; Dapr; differentiation associated protein; Differentiation-associated protein; PH domain-containing family M member 3; pleckstrin homology domain containing M3; pleckstrin homology domain containing, family M, member 1-like; pleckstrin homology domain containing, family M, member 3; pleckstrin homology domain-containing family M member 3; PLEKHM1L; Plekhm3; RGD1307151
Gene Symbols PLEKHM3
Host Species Rabbit
Immunogen A 13 amino acid peptide from near the carboxy terminus of human PLEKHM3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 241075, 316455, 389072
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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