PLEKHM3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8245	100 μL

Catalog No. 50-198-8245 Supplier Bioss Supplier No. BS8064R

Description

Rabbit Polyclonal Antibody

PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.

Specifications

• Antigen: PLEKHM3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: PLEKHM3
• Gene Accession No.: Q6ZWE6
• Gene Alias: 9430067K14Rik; A230102O09Rik; AI449570; DAPR; Differentiation associated protein; Differentiation-associated protein; PH domain-containing family M member 3; pleckstrin homology domain containing M3; pleckstrin homology domain containing, family M, member 1-like; pleckstrin homology domain containing, family M, member 3; Pleckstrin homology domain-containing family M member 3; PLEKHM1L; PLEKHM3; RGD1307151
• Gene Symbols: PLEKHM3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human PLEKHM3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 389072
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG