Invitrogen™ Plexin-A1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547612

Catalog No. PIPA547612

Description

In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) Plexin A2 and rmPlexin A3 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt].

Specifications

• Antigen: Plexin-A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLXNA1
• Gene Alias: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18844, 5361
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P70206, Q9UIW2
• Gene Symbols: PLXNA1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Plexin A1 Ser28-Pro1242.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG