Plexin A1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2692R

Catalog No. 50-198-4905

Description

Plexins are single membrane-spanning signaling proteins encompassing Plexin A1, A2, A3, and A4. Plexins form a complex with neuropilin-1 and -2 and the cell adhesion protein L1 to form a functional receptor for chemorepellent semaphorins. The GTPase Rnd1 binds to the cytoplasmic domain of Plexin A1 to trigger redistribution and depolymerization of actin filaments resulting in cytoskeletal collapse. In contrast, the GTPase RhoD blocks Rnd1-mediated Plexin A1 activation and repulsion of sympathetic axons by Sema3A.

Specifications

• Antigen: Plexin A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLXNA1
• Gene Alias: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; Plexin-A1; PLXN1; Plxna1; RGD1560871; Semaphorin receptor NOV
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5361
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9UIW2
• Gene Symbols: PLXNA1
• Immunogen: KLH conjugated synthetic peptide derived from human Plexin A1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG