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Plexin A1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984905
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100 μL
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50-198-4905 100 μL
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Catalog No. 50-198-4905 Supplier Bioss Supplier No. BS2692R
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Description

Rabbit Polyclonal Antibody

Plexins are single membrane-spanning signaling proteins encompassing Plexin A1, A2, A3, and A4. Plexins form a complex with neuropilin-1 and -2 and the cell adhesion protein L1 to form a functional receptor for chemorepellent semaphorins. The GTPase Rnd1 binds to the cytoplasmic domain of Plexin A1 to trigger redistribution and depolymerization of actin filaments resulting in cytoskeletal collapse. In contrast, the GTPase RhoD blocks Rnd1-mediated Plexin A1 activation and repulsion of sympathetic axons by Sema3A.

Specifications

Antigen Plexin A1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PLXNA1
Gene Accession No. Q9UIW2
Gene Alias 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; Plexin-A1; PLXN1; Plxna1; RGD1560871; Semaphorin receptor NOV
Gene Symbols PLXNA1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Plexin A1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5361
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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