Plexin-A3 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304473AT

Catalog No. 50-156-7812

Description

The recommended shelf life for this product is 1 year from date of receipt.

Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Specifications

• Antigen: Plexin-A3
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: P51805
• Gene Symbols: PLXNA3
• Immunogen: Between 1050 and 1100
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PLXNA3
• Gene Alias: Plxn3, PLXN4, PLXNA3, SEX, XAP-6, HSSEXGENE, plexin A3, plexin-4, Plexin-4, plexin-A3, Plxn3, PLXN3, PLXN4, Semaphorin receptor SEX, Sex chromosome X transmembrane protein of HGF receptor family 3, SEXPLEXIN-A3,6.3, XAP-6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55558
• Content And Storage: 4° C
• Form: Liquid