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Plexin A3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981796
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50-198-1796 100 μL
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Catalog No. 50-198-1796 Supplier Bioss Supplier No. BS11934R
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Description

Rabbit Polyclonal Antibody

Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Specifications

Antigen Plexin A3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Plxna3
Gene Accession No. P51805
Gene Alias 6.3; HSSEXGENE; mKIAA4078; PlexA3; plexin 3; Plexin 4, SEX, homolog to the cMet/HGF receptors; plexin A3; Plexin-4; Plexin-A3; Plxa3; Plxn3; PLXN4; Plxna3; Semaphorin receptor SEX; SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; SEXPLEXIN-A3; XAP-6
Gene Symbols Plxna3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Plexin A3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55558
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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