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Invitrogen™ PLOD2 Monoclonal Antibody (OTI6D1)
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Catalog No. PIMA526585
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100 μL
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PIMA526585 100 μL
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Catalog No. PIMA526585 Supplier Invitrogen™ Supplier No. MA526585
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Description

Mouse Monoclonal Antibody

PLOD2 Monoclonal Antibody for IHC (P), Western Blot

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLOD2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI6D1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Plod2
Gene Accession No. O00469
Gene Alias BRKS2; D530025C14Rik; LH2; LH2; lysyl hydroxylase 2; lysine hydroxylase 2; lysyl hydroxlase 2; lysyl hydroxylase 2; Plod2; Plod-2; procollagen lysine, 2-oxoglutarate 5-dioxygenase 2; Procollagen-lysine 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2; procollagen-lysine 2-oxoglutarate 5-dioxygenase 2; procollagen-lysine 5-dioxygenase; Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; telopeptide lysyl hydroxylase; TLH
Gene Symbols Plod2
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 359-640 of PLOD2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5352
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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