PLOD2 Mouse anti-Human, Clone: 1H9E1, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 663421IG150UL

Catalog No. 50-173-6773

Description

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PLOD2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00469
• Gene Symbols: PLOD2
• Immunogen: PLOD2 Fusion Protein Ag5779
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgA

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 1H9E1
• Conjugate: Unconjugated
• Gene: PLOD2
• Gene Alias: LH2, Lysyl hydroxylase 2, PLOD2, TLH
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5352
• Content And Storage: -20°C
• Form: Liquid