PLOD2 Mouse anti-Human, Clone: OTI6D1, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-6382	100 μg

Catalog No. 50-166-6382 Supplier OriGene Supplier No. CF803224

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PLOD2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6D1
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: PLOD2
• Gene Accession No.: O00469
• Gene Alias: BRKS2, LH2, TLH
• Gene Symbols: PLOD2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 359-640 of human PLOD2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5352
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1