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PLOD2 Mouse anti-Human, Clone: OTI7G5, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF803225

Encompass_Preferred

Catalog No. 50-166-6383


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

PLOD2
Monoclonal
Unconjugated
PLOD2
BRKS2, LH2, TLH
Mouse
Affinity Chromatography
RUO
5352
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI7G5
PBS with 8% trehalose and no preservative; pH 7.3
O00469
PLOD2
Human recombit protein fragment corresponding to amino acids 359-640 of human PLOD2 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG2a
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