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Tocris Bioscience™ PLpro inhibitor 19
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Catalog No. 75055
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5 mg
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75-055 5 mg
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Catalog No. 75-055 Supplier Tocris Bioscience™ Supplier No. 7505/5
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SARS-CoV-2 PLpro and replication inhibitor

PLpro inhibitor 19 is a SARS-CoV-2 inhibitor that inhibits viral replication and PLpro enzymatic activity in vitro (IC50 values are 0.18 μM and 0.44 μM respectively). PLpro inhibitor 19 is selective for PLpro over human deubiquitinating enzymes (DUBs) and DUB-like proteases and displays no cytotoxicity at up to 10 μM.

Specifications

Chemical Name or Material (R)-N-(3-Fluoro-5-((1-(1-(naphthalen-1-yl)ethyl)piperidine-4-carboxamido)methyl)phenyl)-4-methylpiperazine-1-carboxamide
Quantity 5 mg
Target Papain-like Protease
Molecular Formula C31H38FN5O2
Purity 0.98
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