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Invitrogen™ PLS3 Polyclonal Antibody
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Catalog No. PIPA554206
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100 μL
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PIPA554206 100 μL
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Catalog No. PIPA554206 Supplier Invitrogen™ Supplier No. PA554206
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PAKFSLVGIG GQDLNDGNQT LTLALVWQLM RRYTLNVLED LGDGQKANDD IIVNWVNRTL SEAGKSTSIQ SFKDKTISSS LAVVDLIDAI QPGCINYDLV KSGNLTEDDK HNNAKYAVSM ARRIGARVYA LPEDLVEVKP GAPHR Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 90%.

Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLS3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PLS3
Gene Accession No. P13797
Gene Alias AI115446; AL024105; BMND18; LOW QUALITY PROTEIN: plastin-3; MGC128570 protein; plastin 3; plastin 3 (T isoform); plastin 3 (T-isoform); plastin 3, T; plastin-3; PLS3; T fimbrin; T plastin; T-fimbrin; T-plastin
Gene Symbols PLS3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PLS3. Recombinant protein control fragment (Product #RP-98847).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5358
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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