Invitrogen™ PLSCR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527590

Catalog No. PIPA527590

Description

Recommended positive controls: H1299, mouse stomach. Predicted reactivity: Mouse (94%), Rat (94%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt].

Specifications

• Antigen: PLSCR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Plscr3
• Gene Alias: 2210403O21Rik; 2610037N06Rik; Ca 2+ dependent phospholipid scramblase 3; ca(2+)-dependent phospholipid scramblase 3; ESTM3; LOW QUALITY PROTEIN: phospholipid scramblase 3; LOW QUALITY PROTEIN: phospholipid scramblase 3; phospholipid scramblase 3; phospholipid scramblase 3; PL scramblase 3; Pls3; Plscr3; Unknown (protein for MGC:138060); X83310
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57048, 70310
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.77 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9JIZ9, Q9NRY6
• Gene Symbols: Plscr3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PLSCR3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG