Invitrogen™ PLSCR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544769

Catalog No. PIPA544769

Description

Peptide sequence: GCGTDTNFEV KTRDESRSVG RISKQWGGLV REALTDADDF GLQFPLDLDV Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%.

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt].

Specifications

• Antigen: PLSCR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Plscr3
• Gene Alias: 2210403O21Rik; 2610037N06Rik; Ca 2+ dependent phospholipid scramblase 3; ca(2+)-dependent phospholipid scramblase 3; ESTM3; LOW QUALITY PROTEIN: phospholipid scramblase 3; LOW QUALITY PROTEIN: phospholipid scramblase 3; phospholipid scramblase 3; phospholipid scramblase 3; PL scramblase 3; Pls3; Plscr3; Unknown (protein for MGC:138060); X83310
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57048
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9NRY6
• Gene Symbols: Plscr3
• Immunogen: Synthetic peptide directed towards the middle region of human PLSCR3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov