Invitrogen™ PLXNB2 Monoclonal Antibody (537237)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524237

Catalog No. PIMA524237

Description

In direct ELISAs, no cross-reactivity with recombinant human Plexin A4, B1, B3, C1, D1, or recombinant mouse Plexin A1, A2, or A3 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.

Specifications

• Antigen: PLXNB2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O15031
• Gene Symbols: PLXNB2
• Immunogen: CHO-derived recombinant human Plexin B2 Leu20-Arg1160.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: 537237
• Conjugate: Unconjugated
• Gene: PLXNB2
• Gene Alias: Debt; differentially expressed in brain tumors; dJ402G11.3; KIAA0315; MM1; MM1KIAA0315dJ402G11.3; Nbla00445; PLEXB2; plexin B2; plexin-B2; PLXNB2
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 23654
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized