Invitrogen™ PLXND1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143749

Catalog No. PIPA5143749

Description

The antibody detects 250, 215, and 195 kDa bands corresponding to the apparent molecular mass of Plexin D1 variants in human umbilical vein endothelial cells.

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. [UniProt].

Specifications

• Antigen: PLXND1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLXND1
• Gene Alias: 6230425C21Rik; b2b1863Clo; b2b553Clo; KIAA0620; MGC75353; PLEXD1; plexin D1; plexin-D1; Plxnd1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23129, 312652, 67784
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: Q3UH93, Q9Y4D7
• Gene Symbols: PLXND1
• Immunogen: Plexin D1 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the semaphorin domain from human Plexin D1. This sequence is well conserved in rat and mouse Plexin D1, and has low homology to other Plexin family members.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG