Invitrogen™ PML Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580909

Catalog No. PIPA580909

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human PML/RNF71/TRIM19.

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

• Antigen: PML
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PML
• Gene Alias: 1200009E24Rik; AI661194; MYL; Pml; PML/RARA fusion; pml1; PP8675; probable transcription factor PML; promyelocytic leukemia; promyelocytic leukemia protein; promyelocytic leukemia, inducer of; protein PML; RGD1562602; RING finger protein 71; RNF71; TRIM19; tripartite motif protein TRIM19; tripartite motif-containing protein 19
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5371
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P29590
• Gene Symbols: PML
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human PML/RNF71/TRIM19.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov