Invitrogen™ PMP70 Monoclonal Antibody (CL2524)

Catalog No.	Quantity
PIMA531368	100 μL

Catalog No. PIMA531368 Supplier Invitrogen™ Supplier No. MA531368

Description

Mouse Monoclonal Antibody

Immunogen sequence: MVSQQEKGIE GVQVIPLIPG AGEIIIADNI IKFDHVPLAT PNGDVLIRDL NFEVRSGANV LICGP Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 87%.

Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum' disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.

Specifications

• Antigen: PMP70
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Monoclonal
• Clone: CL2524
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: ABCD3
• Gene Accession No.: P28288
• Gene Alias: 68 kDa peroxisomal membrane protein; 70 kDa peroxisomal membrane protein; 70-kDa peroxisomal membrane protein; ABC43; ABCD3; AI313901; ATP binding cassette subfamily D member 3; ATP-binding cassette sub-family D member 3; ATP-binding cassette, subfamily D (ALD), member 3; ATP-binding cassette, sub-family D (ALD), member 3; AU018866; AW146054; CBAS5; dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); Peroxisomal membrane protein 1; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); peroxisomal membrane protein, 70 kDa; Peroxisomal membrane protein-1 (70kD); PMP68; Pmp70; Pxmp1; ZWS2
• Gene Symbols: ABCD3
• Host Species: Mouse
• Immunogen: Recombinant protein fragment of Human ABCD3 (Product #RP-102611)
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5825
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1