Invitrogen™ PMP70 Polyclonal Antibody, Biotin

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142389

Catalog No. PIPA5142389

Description

Additional Information: This antibody is expected to recognize one isoform (NP_002849.1) only. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.

Specifications

• Antigen: PMP70
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: ABCD3
• Gene Alias: 68 kDa peroxisomal membrane protein; 70 kDa peroxisomal membrane protein; 70-kDa peroxisomal membrane protein; ABC43; ABCD3; AI313901; ATP binding cassette subfamily D member 3; ATP-binding cassette sub-family D member 3; ATP-binding cassette, subfamily D (ALD), member 3; ATP-binding cassette, sub-family D (ALD), member 3; AU018866; AW146054; CBAS5; dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); Peroxisomal membrane protein 1; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); peroxisomal membrane protein, 70 kDa; Peroxisomal membrane protein-1 (70kD); PMP68; Pmp70; Pxmp1; ZWS2
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 5825
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P28288
• Gene Symbols: ABCD3
• Immunogen: Peptide with sequence C-PDGREDQKRKGISD.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG