PMS2Mouse anti-Chimpanzee, Hamster, Human, Mouse, Rat, Clone: 1204, Rockland™

Mouse Monoclonal Antibody

Supplier:  Rockland Immunochemicals 200301864

Catalog No. 50-199-0537

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2. BLAST analysis indicates that this sequence is 100% identical for human, mouse, rat and chimpanzee. No specific information is available for reactivity with PMS2 protein from other sources.

PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.

Specifications

• Antigen: PMS2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: P54278, P54279
• Gene Symbols: PMS2
• Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with recombinant human PMS2 corresponding to the first 133 amino acid residues of the protein. The clone was produced using conventional hybridoma technology.
• Regulatory Status: RUO
• Gene ID (Entrez): 100755917, 18861, 288479, 5395, 742579
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 1204
• Conjugate: Unconjugated
• Gene: PMS2
• Gene Alias: AW555130; DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; Mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 postmeiotic segregation increased 2; PMS2CL; PMSL2; postmeiotic segregation increased 2 (S. cerevisiae); postmeiotic segregation increased 2 nirs variant 6
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Chimpanzee, Hamster, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ