Invitrogen™ PNLDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562535

Catalog No. PIPA562535

Description

Immunogen sequence: VGHNMMMDLL HLHEKFFRPL PESYDQFKQN IHSLFPVLID TKSVTKDIWK EMNFPRVSNL SEVYEVLNSD LNPT Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells. [UniProt].

Specifications

• Antigen: PNLDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PNLDC1
• Gene Alias: HsPNLDC1; PARN like, ribonuclease domain containing 1; PARN-like domain-containing protein 1; PNLDC1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease domain-containing protein 1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1; Poly(A)-specific ribonuclease PNLDC1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 154197
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.12 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NA58
• Gene Symbols: PNLDC1
• Immunogen: Recombinant protein corresponding to Human PNLDC1. Recombinant protein control fragment (Product #RP-101348).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov