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PNMA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501730948 Shop All Proteintech Group Inc Products
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50-173-0948 150 μL
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Catalog No. 50-173-0948 Supplier Proteintech Group Inc Supplier No. 164451AP150UL
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Description

Rabbit Polyclonal Antibody

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.

Specifications

Antigen PNMA2
Applications Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PNMA2
Gene Accession No. Q8BHK0, Q9UL42
Gene Alias 40 kDa neuronal protein, KIAA0883, MA2, MM2, Onconeuronal antigen Ma2, paraneoplastic antigen MA2, PNMA2, RGAG2
Gene Symbols PNMA2
Host Species Rabbit
Immunogen PNMA2 Fusion Protein Ag10289
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10687, 239157, 305977
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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