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Invitrogen™ PNN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551569

Catalog No. PIPA551569


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Description

Description

Immunogen sequence: EQKVELAQLQ EEWNEHNAKI IKYIRTKTKP HLFYIPGRMC PATQKLIEES QRKMNALFEG RRIEFAEQIN KMEARPRRQS MKEKEHQVVR NEEQKAEQEE GKVAQREEEL EETGNQHNDV EIEEAGEEEE KEIAIVHSDA EKE Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PNN
Polyclonal
Unconjugated
PNN
140 kDa nuclear and cell adhesion-related phosphoprotein; AU045199; D12Ertd512e; Desmosome-associated protein; domain-rich serine protein; DRS; DRS protein; DRSP; fb24d03; Melanoma metastasis clone A protein; memA; neutrophil protein; nuclear protein SDK3; Pinin; pinin, desmosome associated protein; PNN; PNN protein; SDK3; SR-like protein; wu:fb24d03
Rabbit
Antigen affinity chromatography
RUO
5411
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9H307
PNN
Recombinant protein corresponding to Human PNN. Recombinant protein control fragment (Product #RP-88923).
100 μL
Primary
Human
Antibody
IgG
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