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Invitrogen™ PNR Polyclonal Antibody
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Catalog No. PIPA120600
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25 μg
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Catalog No. Quantity
PIPA120600 25 μg
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Catalog No. PIPA120600 Supplier Invitrogen™ Supplier No. PA120600
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Description

Rabbit Polyclonal Antibody

PA1-20600 detects PNR in Human samples.

NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PNR
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene NR2E3
Gene Accession No. Q9Y5X4
Gene Alias A930035N01Rik; ESCS; MGC138414; MGC138416; Nr2e3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; rd7; retinal degeneration 7; Retina-specific nuclear receptor; Rnr; RP11-295F4.5; RP37; taR-5
Gene Symbols NR2E3
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide near N-terminus of human NR2E3.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10002
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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