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  5. Tocris Bioscience™ PNU 120596

Tocris Bioscience™ PNU 120596
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Catalog No. 24985
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25 mg
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24-985 5 mg
24-982-5 25 mg
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Catalog No. 24-985 Supplier Tocris Bioscience™ Supplier No. 2498/5
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Description

Positive allosteric modulator of α7 nAChRs; active in vivo

PNU 120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.

Specifications

Chemical Name or Material N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
CAS 501925-31-1
Assay Percent Range >99%
Quantity 5 mg
Molecular Formula C13H14ClN3O4
Formula Weight Observed MW: 311.72
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