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  5. Tocris Bioscience™ PNU 37883 hydrochloride

Tocris Bioscience™ PNU 37883 hydrochloride
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Catalog No. 209510
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Vascular Kir6 (KATP) channel blocker

Novel antagonist selective for the vascular form of Kir6 (KATP) channel; inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Inhibits blood vessel relaxation and hypotension induced by pinacidil in vivo. Displays weak diuretic effects.

Chemical Identifiers

CAS 57568-80-6
Molecular Formula C21H36ClN3O

Specifications

Quantity 10 mg
Formula Weight 381.98
Purity >99%
Molecular Weight (g/mol) 381.989
Chemical Name or Material PNU 37883 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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