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  5. Tocris Bioscience™ PNU 37883 hydrochloride

Tocris Bioscience™ PNU 37883 hydrochloride
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Catalog No. 209550
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20-955-0 50 mg
20-951-0 10 mg
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Catalog No. 20-955-0 Supplier Tocris Bioscience™ Supplier No. 2095/50
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Description

Vascular Kir6 (KATP) channel blocker

Novel antagonist selective for the vascular form of Kir6 (KATP) channel; inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Inhibits blood vessel relaxation and hypotension induced by pinacidil in vivo. Displays weak diuretic effects.

Chemical Identifiers

CAS 57568-80-6
Molecular Formula C21H36ClN3O

Specifications

Quantity 50 mg
Formula Weight 381.98
Purity >99%
Molecular Weight (g/mol) 381.989
Chemical Name or Material PNU 37883 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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