PODN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9910	Proteintech Group Inc 150141AP150UL	150 μL

Description

Non-collagenous proteins of the small leucine-rich repeat (SLR) protein family are considered important components of the extracellular matrix. The extracellular matrix plays an integral role in the pivotal processes of development, tissue repair and metastasis by regulating cell proliferation, differentiation, adhesion and migration. Podocan, also known as PCAN, SLRR5A or PODN, is a 613 amino acid secreted protein belonging to the small leucine-rich proteoglycan (SLRP) family and the class V subfamily. Expressed in kidney, heart, liver, pancreas and vascular smooth muscle cells, Podocan exists as three alternatively spliced isoforms containing twenty LRR (leucine-rich repeats), a unique N-terminal cysteine-rich cluster pattern and a highly acidic C-terminal domain. Podocan is considered a glycoprotein containing N-linked oligosaccharides that may be involved in growth regulation in cardiovascular tissues. Encoded by a gene located on human chromosome 1, Podocan interacts type I collagen (COL1).

Specifications

• Antigen: PODN
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q7TQ62, Q7Z5L7
• Gene ID (Entrez): 127435, 242608
• Immunogen: PODN Fusion Protein Ag6964
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PODN

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: PCAN, PODN, podocan, SLRR5A
• Gene Symbols: Podn
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody