PODN Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2392	100 μL

Catalog No. 50-198-2392 Supplier Bioss Supplier No. BS12749R

Description

Rabbit Polyclonal Antibody

Non-collagenous proteins of the small leucine-rich repeat (SLR) protein family are considered important components of the extracellular matrix. The extracellular matrix plays an integral role in the pivotal processes of development, tissue repair and metastasis by regulating cell proliferation, differentiation, adhesion and migration. Podocan, also known as PCAN, SLRR5A or PODN, is a 613 amino acid secreted protein belonging to the small leucine-rich proteoglycan (SLRP) family and the class V subfamily. Expressed in kidney, heart, liver, pancreas and vascular smooth muscle cells, Podocan exists as three alternatively spliced isoforms containing twenty LRR (leucine-rich repeats), a unique N-terminal cysteine-rich cluster pattern and a highly acidic C-terminal domain. Podocan is considered a glycoprotein containing N-linked oligosaccharides that may be involved in growth regulation in cardiovascular tissues. Encoded by a gene located on human chromosome 1, Podocan interacts type I collagen (COL1).

Specifications

• Antigen: PODN
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Podn
• Gene Accession No.: Q7Z5L7
• Gene Alias: 9430070G18; PCAN; PODN; Podocan; podocan proteoglycan; PRO332; SLRR5A; UNQ293; UNQ293/PRO332
• Gene Symbols: Podn
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human PODN.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 127435
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG