Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Podoplanin Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
$518.60
Specifications
Antigen | Podoplanin |
---|---|
Concentration | 0.3 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-7325
![]() ![]() |
Proteintech Group Inc
116291AP150UL |
150 μL |
Each of 1 for $518.60
|
|
|||||
Description
The antibody is specific to Podoplanin.
Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.Specifications
Podoplanin | |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
Q86YL7 | |
10630 | |
Podoplanin Fusion Protein Ag2201 | |
Primary | |
-20°C | |
PDPN |
0.3 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
AGGRUS, D2 40, D2 40,M2A, Glycoprotein 36, GP36, Gp38, GP40, HT1A 1, M2A, OTS8, PA2.26, PA2.26 antigen, PDPN, podoplanin, PSEC0025, T1 alpha, T1A, T1A 2 | |
PDPN | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title