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Description
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq]
Specifications
Specifications
| Antigen | PODXL |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | 2A4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant human PODXL. |
| Dilution | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS (0.05% BSA, 0.05% sodium azide). |
| Gene Alias | Gp200/MGC138240/PC/PCLP |
| Gene Symbols | PODXL |
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