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Invitrogen™ POFUT1 Polyclonal Antibody
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Catalog No. PIPA5142902
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100 μg
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PIPA5142902 100 μg
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Catalog No. PIPA5142902 Supplier Invitrogen™ Supplier No. PA5142902
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_056167.1; NP_758436.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch; mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POFUT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene POFUT1
Gene Accession No. Q9H488
Gene Alias DDD2; FUT12; GDP-fucose protein O-fucosyltransferase 1; KIAA0180; mKIAA0180; o-fucosyltransferase protein; O-Fuc-T; OFUCT1; O-FucT-1; O-FucT-1a; O-FucT-1b; O-FUT; peptide-O-fucosyltransferase 1; Pofut1; pofut1 {ECO:0000312; protein O-fucosyltransferase 1; protein O-fucosyltransferase 1 isoform 1 precursor; protein O-fucosyltransferase 1a; protein O-fucosyltransferase 1b; protein-O-fucosyltransferase 1; RGD:1303001}; zgc:110472
Gene Symbols POFUT1
Host Species Goat
Immunogen Peptide with sequence C-TNLHVSYQKYFKLEP.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23509
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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