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Invitrogen™ POFUT1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5119370
This item is not returnable.
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Description
POFUT1 Polyclonal Antibody for Western Blot, IHC (P)
POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch; mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.
Specifications
POFUT1 | |
Polyclonal | |
Unconjugated | |
POFUT1 | |
DDD2; FUT12; GDP-fucose protein O-fucosyltransferase 1; KIAA0180; mKIAA0180; o-fucosyltransferase protein; O-Fuc-T; OFUCT1; O-FucT-1; O-FucT-1a; O-FucT-1b; O-FUT; peptide-O-fucosyltransferase 1; Pofut1; pofut1 {ECO:0000312; protein O-fucosyltransferase 1; protein O-fucosyltransferase 1 isoform 1 precursor; protein O-fucosyltransferase 1a; protein O-fucosyltransferase 1b; protein-O-fucosyltransferase 1; RGD:1303001}; zgc:110472 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
23509 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
500 μg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
Q9H488 | |
POFUT1 | |
Recombinant protein O-Fucosyltransferase 1. The antigen corresponds to amino acid range 238-388 of the target protein. | |
200 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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