Invitrogen™ POGK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556804

Catalog No. PIPA556804

Description

Immunogen sequence: QLQNAHAMRR AFRGPKNGRF ALVDQRVAEY VRYMQAKGDP ITREAMQLKA LEIAQEMNIP EKGFKASLGW CRRMMRRYDL SLRHKVPVPQ HLPEDLTEKL VTYQRSVLAL RRAHDYEVAQ MGNADETPIC LEVPSRVTV Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases.

Specifications

• Antigen: POGK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POGK
• Gene Alias: BASS2; EGK_01919; KIAA1513; KRAB box domain containing 2; KRBOX2; LST003; POGK; pogo transposable element derived with KRAB domain; pogo transposable element with KRAB domain; SLTP003
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57645
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9P215
• Gene Symbols: POGK
• Immunogen: Recombinant protein corresponding to Human POGK. Recombinant protein control fragment (Product #RP-89161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov