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Invitrogen™ POLB Polyclonal Antibody
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Catalog No. PIPA583950
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100 μL
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PIPA583950 100 μL
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Catalog No. PIPA583950 Supplier Invitrogen™ Supplier No. PA583950
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YCGVLYFTGS DIFNKNMRAH ALEKGFTINE YTIRPLGVTG VAGEPLPVDS EKDIFDYIQW KYREPKDRSE Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.

DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLB
Gene Accession No. P06746
Gene Alias A430088C08Rik; DNA pol beta; DNA polymerase beta; DNA polymerase beta subunit; DNA-directed DNA polymerase beta; hypothetical protein LOC614688; LOW QUALITY PROTEIN: DNA polymerase beta; MGC125976; POL B; Pol beta; POLB; polb.S; polymerase (DNA directed), beta; polymerase (DNA directed), beta S homeolog; polymerase (DNA) beta; polymerase B; polymerase-beta; wu:fa97a05; XELAEV_18020165mg; zgc:109924
Gene Symbols POLB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLB. Recombinant protein control fragment (Product #RP-103044).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5423
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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