Invitrogen™ POLG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598070

Catalog No. PIPA598070

Description

POLG Polyclonal Antibody for Western Blot, ELISA

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: POLG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLG
• Gene Alias: AA409516; DNA polymerase gamma; DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha); DNA polymerase gamma, catalytic subunit; DNA polymerase subunit gamma-1; DNA-directed DNA polymerase gamma; FLJ27114; MDP1; Mip1; MIRAS; Mitochondrial DNA polymerase catalytic subunit; mitochondrial DNA polymerase gamma; mitochondrial DNA polymerase gamma catalytic subunit; mitochondrial DNA polymerase-gamma; mitochondrial polymerase gamma; MTDPS4A; MTDPS4B; PEO; Pol gamma; Polg; POLG1; POLGA; PolG-alpha; polymerase (DNA directed), gamma; polymerase (DNA) gamma, catalytic subunit; polymerase, gamma; SANDO; SCAE; truncated mitochondrial DNA polymerase gamma catalytic subunit
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5428
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P54098
• Gene Symbols: POLG
• Immunogen: Recombinant Human DNA polymerase subunit gamma-1 protein (446-590AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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