Invitrogen™ POLG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575881

Catalog No. PIPA575881

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Specifications

• Antigen: POLG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLG2
• Gene Alias: AA409516; DNA polymerase gamma; DNA polymerase gamma 2, accessory subunit; DNA polymerase gamma accessory 55 kDa subunit; DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha); DNA polymerase gamma, catalytic subunit; DNA polymerase subunit gamma-1; DNA polymerase subunit gamma-2, mitochondrial; DNA-directed DNA polymerase gamma; HP55; MDP1; Mip1; MIRAS; Mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase catalytic subunit; mitochondrial DNA polymerase gamma; mitochondrial DNA polymerase gamma catalytic subunit; mitochondrial DNA polymerase subunit gamma-2; mitochondrial DNA polymerase, accessory subunit; mitochondrial DNA polymerase-gamma; mitochondrial polymerase gamma; mitochondrial polymerase gamma 2; MTDPS4A; MTDPS4B; MTPOLB; p55; PEO; PEOA4; Pol gamma; POLB; POLG; POLG1; Polg2; POLGA; PolG-alpha; POLGB; polG-beta; polymerase (DNA directed), gamma; polymerase (DNA directed), gamma 2, accessory subunit; polymerase (DNA) gamma 2, accessory subunit; polymerase (DNA) gamma, catalytic subunit; polymerase, gamma; polymerase, gamma 2; SANDO; SCAE; truncated mitochondrial DNA polymerase gamma catalytic subunit
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11232, 303612, 50776
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9QZM2, Q9UHN1
• Gene Symbols: POLG2
• Immunogen: Synthetic peptide corresponding to residues in Human POLG2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG